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Combination therapy with cilostazol, aripiprazole, and donepezil protects neuronal cells from β-amyloid neurotoxicity through synergistically enhanced SIRT1 expression

Alzheimer’s disease (AD) is a multi-faceted neurodegenerative disease. Thus, current therapeutic strategies require multitarget-drug combinations to treat or prevent the disease. At the present time, single drugs have proven to be inadequate in terms of addressing the multifactorial pathology of AD,...

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Publicat a:Korean J Physiol Pharmacol
Autors principals: Heo, Hye Jin, Park, So Youn, Lee, Yi Sle, Shin, Hwa Kyoung, Hong, Ki Whan, Kim, Chi Dae
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317180/
https://ncbi.nlm.nih.gov/pubmed/32587124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2020.24.4.299
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