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Neuroprotection by aripiprazole against β-amyloid-induced toxicity by P-CK2α activation via inhibition of GSK-3β

Psychosis is reported over 30% of patients with Alzheimer's disease (AD) in clinics. Aripiprazole is an atypical antipsychotic drug with partial agonist activity at the D(2) dopamine and 5-HT(1A) receptors with low side-effect profile. We identified aripiprazole is able to overcome the amyloid-...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Park, So Youn, Shin, Hwa Kyoung, Lee, Won Suk, Bae, Sun Sik, Kim, Koanhoi, Hong, Ki Whan, Kim, Chi Dae
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746390/
https://ncbi.nlm.nih.gov/pubmed/29299155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22777
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