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Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with high metastatic rates and poor overall patient survival. There are currently no effective therapies, underscoring the pressing need to define the molecular etiologies that underlie MPNST progressio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurooncol Adv
Päätekijät: Godec, Abigail, Jayasinghe, Reyka, Chrisinger, John S A, Prudner, Bethany, Ball, Tyler, Wang, Yuxi, Srihari, Divya, Kaushal, Madhurima, Dietz, Hilary, Zhang, Xiaochun, Pekmezci, Melike, Dahiya, Sonika, Tao, Yu, Luo, Jinqin, Van Tine, Brian A, Ding, Li, Gutmann, David H, Hirbe, Angela C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317063/
https://ncbi.nlm.nih.gov/pubmed/32642734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz026
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