Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with high metastatic rates and poor overall patient survival. There are currently no effective therapies, underscoring the pressing need to define the molecular etiologies that underlie MPNST progressio...

詳細記述

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書誌詳細
出版年:Neurooncol Adv
主要な著者: Godec, Abigail, Jayasinghe, Reyka, Chrisinger, John S A, Prudner, Bethany, Ball, Tyler, Wang, Yuxi, Srihari, Divya, Kaushal, Madhurima, Dietz, Hilary, Zhang, Xiaochun, Pekmezci, Melike, Dahiya, Sonika, Tao, Yu, Luo, Jinqin, Van Tine, Brian A, Ding, Li, Gutmann, David H, Hirbe, Angela C
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
Supplement Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317063/
https://ncbi.nlm.nih.gov/pubmed/32642734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz026
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