Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with high metastatic rates and poor overall patient survival. There are currently no effective therapies, underscoring the pressing need to define the molecular etiologies that underlie MPNST progressio...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Godec, Abigail, Jayasinghe, Reyka, Chrisinger, John S A, Prudner, Bethany, Ball, Tyler, Wang, Yuxi, Srihari, Divya, Kaushal, Madhurima, Dietz, Hilary, Zhang, Xiaochun, Pekmezci, Melike, Dahiya, Sonika, Tao, Yu, Luo, Jinqin, Van Tine, Brian A, Ding, Li, Gutmann, David H, Hirbe, Angela C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Supplement Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317063/
https://ncbi.nlm.nih.gov/pubmed/32642734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz026
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