Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

Ischemia reperfusion (IR) injury may be attenuated through succinate dehydrogenase (SDH) inhibition by dimethyl malonate (DiMAL). Whether SDH inhibition yields protection in diabetic individuals and translates into human cardiac tissue remain unknown. In isolated perfused hearts from 24 weeks old ma...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Jespersen, Nichlas Riise, Hjortbak, Marie Vognstoft, Lassen, Thomas Ravn, Støttrup, Nicolaj Brejnholt, Johnsen, Jacob, Tonnesen, Pernille Tilma, Larsen, Steen, Kimose, Hans-Henrik, Bøtker, Hans Erik
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316713/
https://ncbi.nlm.nih.gov/pubmed/32587298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67247-4
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