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Cardioprotective effects of empagliflozin after ischemia and reperfusion in rats

The Sodium Glucose Co-Transporter-2 inhibitor, empagliflozin (EMPA), reduces mortality and hospitalisation for heart failure following myocardial infarction irrespective of diabetes status. While the findings suggest an inherent cardioprotective capacity, the mechanism remains unknown. We studied in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seefeldt, Jacob Marthinsen, Lassen, Thomas Ravn, Hjortbak, Marie Vognstoft, Jespersen, Nichlas Riise, Kvist, Frederikke, Hansen, Jakob, Bøtker, Hans Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100147/
https://ncbi.nlm.nih.gov/pubmed/33953281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89149-9
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