The LFA-1 antagonist BIRT377 reverses neuropathic pain in prenatal alcohol-exposed female rats via actions on peripheral and central neuroimmune function in discrete pain-relevant tissue regions.

Previous reports show that moderate prenatal alcohol exposure (PAE) poses a risk factor for developing neuropathic pain following adult-onset peripheral nerve injury in male rats. Recently, evidence suggests that immune-related mechanisms underlying neuropathic pain in females are different compared...

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Dades bibliogràfiques
Publicat a:Brain Behav Immun
Autors principals: Noor, Shahani, Sanchez, Joshua J., Sun, Melody S., Pervin, Zinia, Sanchez, Jacob E., Havard, Mara A., Epler, Lauren T., Nysus, Monique V., Norenberg, Jeffrey P., Wagner, Carston R., Davies, Suzy, Wagner, Jennifer L, Savage, Daniel D., Jantzie, Lauren L., Mellios, Nikolaos, Milligan, Erin. D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316595/
https://ncbi.nlm.nih.gov/pubmed/31918004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.01.002
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