Effects of spinal non-viral interleukin-10 gene therapy formulated with D-mannose in neuropathic interleukin-10 deficient mice: behavioral characterization, mRNA and protein analysis in pain relevant tissues

Studies show that spinal (intrathecal; i.t.) interleukin-10 (IL-10) gene therapy reverses neuropathic pain in animal models, and co-administration with the mannose receptor (MR; CD206) ligand D-mannose (DM) greatly improves therapeutic efficacy. However, the actions of endogenous IL-10 may be requir...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Vanderwall, Arden G., Noor, Shahani, Sun, Melody S., Sanchez, Jacob E., Yang, Xuexian O., Jantzie, Lauren L., Mellios, Nikolaos, Milligan, Erin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857419/
https://ncbi.nlm.nih.gov/pubmed/29113923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.11.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados