The LFA-1 antagonist BIRT377 reverses neuropathic pain in prenatal alcohol-exposed female rats via actions on peripheral and central neuroimmune function in discrete pain-relevant tissue regions.

Previous reports show that moderate prenatal alcohol exposure (PAE) poses a risk factor for developing neuropathic pain following adult-onset peripheral nerve injury in male rats. Recently, evidence suggests that immune-related mechanisms underlying neuropathic pain in females are different compared...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Noor, Shahani, Sanchez, Joshua J., Sun, Melody S., Pervin, Zinia, Sanchez, Jacob E., Havard, Mara A., Epler, Lauren T., Nysus, Monique V., Norenberg, Jeffrey P., Wagner, Carston R., Davies, Suzy, Wagner, Jennifer L, Savage, Daniel D., Jantzie, Lauren L., Mellios, Nikolaos, Milligan, Erin. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316595/
https://ncbi.nlm.nih.gov/pubmed/31918004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.01.002
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