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Role of the ERO1-PDI interaction in oxidative protein folding and disease
Protein folding in the endoplasmic reticulum is an oxidative process that relies on protein disulfide isomerase (PDI) and endoplasmic reticulum oxidase 1 (ERO1). Over 30% of proteins require the chaperone PDI to promote disulfide bond formation. PDI oxidizes cysteines in nascent polypeptides to form...
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| Udgivet i: | Pharmacol Ther |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316501/ https://ncbi.nlm.nih.gov/pubmed/32201313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107525 |
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