Synergistic cooperation of PDI family members in peroxiredoxin 4-driven oxidative protein folding

The mammalian endoplasmic reticulum (ER) harbors disulfide bond-generating enzymes, including Ero1α and peroxiredoxin 4 (Prx4), and nearly 20 members of the protein disulfide isomerase family (PDIs), which together constitute a suitable environment for oxidative protein folding. Here, we clarified t...

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Detalhes bibliográficos
Main Authors: Sato, Yoshimi, Kojima, Rieko, Okumura, Masaki, Hagiwara, Masatoshi, Masui, Shoji, Maegawa, Ken-ichi, Saiki, Masatoshi, Horibe, Tomohisa, Suzuki, Mamoru, Inaba, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744794/
https://ncbi.nlm.nih.gov/pubmed/23949117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02456
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