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Manipulation of oxidative protein folding and PDI redox state in mammalian cells

In the endoplasmic reticulum (ER), disulfide bonds are simultaneously formed in nascent proteins and removed from incorrectly folded or assembled molecules. In this compartment, the redox state must be, therefore, precisely regulated. Here we show that both human Ero1-Lα and Ero1-Lβ (hEROs) facilita...

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Hlavní autoři: Mezghrani, Alexandre, Fassio, Anna, Benham, Adam, Simmen, Thomas, Braakman, Ineke, Sitia, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125306/
https://ncbi.nlm.nih.gov/pubmed/11707400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6288
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