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Manipulation of oxidative protein folding and PDI redox state in mammalian cells

In the endoplasmic reticulum (ER), disulfide bonds are simultaneously formed in nascent proteins and removed from incorrectly folded or assembled molecules. In this compartment, the redox state must be, therefore, precisely regulated. Here we show that both human Ero1-Lα and Ero1-Lβ (hEROs) facilita...

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Detalhes bibliográficos
Main Authors: Mezghrani, Alexandre, Fassio, Anna, Benham, Adam, Simmen, Thomas, Braakman, Ineke, Sitia, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125306/
https://ncbi.nlm.nih.gov/pubmed/11707400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6288
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