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Manipulation of oxidative protein folding and PDI redox state in mammalian cells

In the endoplasmic reticulum (ER), disulfide bonds are simultaneously formed in nascent proteins and removed from incorrectly folded or assembled molecules. In this compartment, the redox state must be, therefore, precisely regulated. Here we show that both human Ero1-Lα and Ero1-Lβ (hEROs) facilita...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Mezghrani, Alexandre, Fassio, Anna, Benham, Adam, Simmen, Thomas, Braakman, Ineke, Sitia, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6288
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