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What have we learned from animal models of idiosyncratic, drug-induced Liver Injury?

INTRODUCTION: Idiosyncratic, drug-induced liver injury (IDILI) continues to plague patients and restrict the use of drugs that are pharmacologically effective. Mechanisms of IDILI are incompletely understood, and a better understanding would reduce speculation and could help to identify safer drug c...

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Опубликовано в: :Expert Opin Drug Metab Toxicol
Главные авторы: Roth, Robert A., Ganey, Patricia E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315440/
https://ncbi.nlm.nih.gov/pubmed/32324077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2020.1760246
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