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Germline burden of rare damaging variants negatively affects human healthspan and lifespan
Heritability of human lifespan is 23–33% as evident from twin studies. Genome-wide association studies explored this question by linking particular alleles to lifespan traits. However, genetic variants identified so far can explain only a small fraction of lifespan heritability in humans. Here, we r...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7314550/ https://ncbi.nlm.nih.gov/pubmed/32254024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53449 |
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