Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions

The neurotoxicity of air pollution is undefined for sex and APOE alleles. These major risk factors of Alzheimer’s disease (AD) were examined in mice given chronic exposure to nPM, a nano-sized subfraction of urban air pollution. In the cerebral cortex, female mice had two-fold more genes responding...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Haghani, Amin, Cacciottolo, Mafalda, Doty, Kevin R, D'Agostino, Carla, Thorwald, Max, Safi, Nikoo, Levine, Morgan E, Sioutas, Constantinos, Town, Terrence C, Forman, Henry Jay, Zhang, Hongqiao, Morgan, Todd E, Finch, Caleb E
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2020
विषय:
Computational and Systems Biology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314548/
https://ncbi.nlm.nih.gov/pubmed/32579111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54822
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