Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions

The neurotoxicity of air pollution is undefined for sex and APOE alleles. These major risk factors of Alzheimer’s disease (AD) were examined in mice given chronic exposure to nPM, a nano-sized subfraction of urban air pollution. In the cerebral cortex, female mice had two-fold more genes responding...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Haghani, Amin, Cacciottolo, Mafalda, Doty, Kevin R, D'Agostino, Carla, Thorwald, Max, Safi, Nikoo, Levine, Morgan E, Sioutas, Constantinos, Town, Terrence C, Forman, Henry Jay, Zhang, Hongqiao, Morgan, Todd E, Finch, Caleb E
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
Предметы:
Computational and Systems Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314548/
https://ncbi.nlm.nih.gov/pubmed/32579111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54822
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы