Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions

The neurotoxicity of air pollution is undefined for sex and APOE alleles. These major risk factors of Alzheimer’s disease (AD) were examined in mice given chronic exposure to nPM, a nano-sized subfraction of urban air pollution. In the cerebral cortex, female mice had two-fold more genes responding...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Haghani, Amin, Cacciottolo, Mafalda, Doty, Kevin R, D'Agostino, Carla, Thorwald, Max, Safi, Nikoo, Levine, Morgan E, Sioutas, Constantinos, Town, Terrence C, Forman, Henry Jay, Zhang, Hongqiao, Morgan, Todd E, Finch, Caleb E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2020
Gaiak:
Computational and Systems Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314548/
https://ncbi.nlm.nih.gov/pubmed/32579111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54822
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