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Structural and chemical trapping of flavin‐oxide intermediates reveals substrate‐directed reaction multiplicity
Though reactive flavin‐N5/C4α‐oxide intermediates can be spectroscopically profiled for some flavin‐assisted enzymatic reactions, their exact chemical configurations are hardly visualized. Structural systems biology and stable isotopic labelling techniques were exploited to correct this stereotypica...
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| Publicado no: | Protein Sci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7314388/ https://ncbi.nlm.nih.gov/pubmed/32362037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3879 |
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