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Targeting of Intracellular TMEM16 Proteins to the Plasma Membrane and Activation by Purinergic Signaling

Anoctamins such as TMEM16A and TMEM16B are Ca(2+)-dependent Cl(−) channels activated through purinergic receptor signaling. TMEM16A (ANO1), TMEM16B (ANO2) and TMEM16F (ANO6) are predominantly expressed at the plasma membrane and are therefore well accessible for functional studies. While TMEM16A and...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Schreiber, Rainer, Ousingsawat, Jiraporn, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312528/
https://ncbi.nlm.nih.gov/pubmed/32517157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114065
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