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CLCA1 Regulates Airway Mucus Production and Ion Secretion Through TMEM16A
TMEM16A, a Ca(2+)-activated chloride channel (CaCC), and its regulator, CLCA1, are associated with inflammatory airway disease and goblet cell metaplasia. CLCA1 is a secreted protein with protease activity that was demonstrated to enhance membrane expression of TMEM16A. Expression of CLCA1 is partic...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8151571/ https://ncbi.nlm.nih.gov/pubmed/34066250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105133 |
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