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Chronic Sulforaphane Administration Inhibits Resistance to the mTOR-Inhibitor Everolimus in Bladder Cancer Cells

Progressive bladder cancer growth is associated with abnormal activation of the mammalian target of the rapamycin (mTOR) pathway, but treatment with an mTOR inhibitor has not been as effective as expected. Rather, resistance develops under chronic drug use, prompting many patients to lower their rel...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Justin, Saira, Rutz, Jochen, Maxeiner, Sebastian, Chun, Felix K.-H., Juengel, Eva, Blaheta, Roman A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312500/
https://ncbi.nlm.nih.gov/pubmed/32512849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114026
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