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Chronic Sulforaphane Administration Inhibits Resistance to the mTOR-Inhibitor Everolimus in Bladder Cancer Cells

Progressive bladder cancer growth is associated with abnormal activation of the mammalian target of the rapamycin (mTOR) pathway, but treatment with an mTOR inhibitor has not been as effective as expected. Rather, resistance develops under chronic drug use, prompting many patients to lower their rel...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Justin, Saira, Rutz, Jochen, Maxeiner, Sebastian, Chun, Felix K.-H., Juengel, Eva, Blaheta, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7312500/
https://ncbi.nlm.nih.gov/pubmed/32512849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21114026
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