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Epoxyeicosatrienoic acid metabolites inhibit Kir4.1/Kir5.1 in the distal convoluted tubule
Cytochrome P-450 (Cyp) epoxygenase-dependent metabolites of arachidonic acid (AA) have been shown to inhibit renal Na(+) transport, and inhibition of Cyp-epoxygenase is associated with salt-sensitive hypertension. We used the patch-clamp technique to examine whether Cyp-epoxygenase-dependent AA meta...
Enregistré dans:
| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7311705/ https://ncbi.nlm.nih.gov/pubmed/32308018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00018.2020 |
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