Loading...

Asymmetry between Activators and Deactivators in Functional Protein Networks

Are “turn-on” and “turn-off” functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study n...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Tareen, Ammar, Wingreen, Ned S., Mukhopadhyay, Ranjan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311538/
https://ncbi.nlm.nih.gov/pubmed/32576941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66699-y
Tags: Add Tag
No Tags, Be the first to tag this record!