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Asymmetry between Activators and Deactivators in Functional Protein Networks

Are “turn-on” and “turn-off” functions in protein-protein interaction networks exact opposites of each other? To answer this question, we implement a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study n...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Tareen, Ammar, Wingreen, Ned S., Mukhopadhyay, Ranjan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311538/
https://ncbi.nlm.nih.gov/pubmed/32576941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66699-y
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