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Hidden long evolutionary memory in a model biochemical network
We introduce a minimal model for the evolution of functional protein-interaction networks using a sequence-based mutational algorithm, and apply the model to study neutral drift in networks that yield oscillatory dynamics. Starting with a functional core module, random evolutionary drift increases n...
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| Published in: | Phys Rev E |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5973509/ https://ncbi.nlm.nih.gov/pubmed/29758653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.97.040401 |
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