β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593

Actinomycetes bacteria produce diverse bioactive molecules that are useful as drug seeds. To improve their yield, researchers often optimize the fermentation medium. However, exactly how the extracellular chemicals present in the medium activate secondary metabolite gene clusters remains unresolved....

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Vydáno v:Sci Rep
Hlavní autoři: Panthee, Suresh, Kito, Naoko, Hayashi, Teruo, Shimizu, Takeshi, Ishikawa, Jun, Hamamoto, Hiroshi, Osada, Hiroyuki, Takahashi, Shunji
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311520/
https://ncbi.nlm.nih.gov/pubmed/32576869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66974-y
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