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β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593

Actinomycetes bacteria produce diverse bioactive molecules that are useful as drug seeds. To improve their yield, researchers often optimize the fermentation medium. However, exactly how the extracellular chemicals present in the medium activate secondary metabolite gene clusters remains unresolved....

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Panthee, Suresh, Kito, Naoko, Hayashi, Teruo, Shimizu, Takeshi, Ishikawa, Jun, Hamamoto, Hiroshi, Osada, Hiroyuki, Takahashi, Shunji
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311520/
https://ncbi.nlm.nih.gov/pubmed/32576869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66974-y
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