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Paramagnetic NMR in drug discovery

The presence of an unpaired electron in paramagnetic molecules generates significant effects in NMR spectra, which can be exploited to provide restraints complementary to those used in standard structure-calculation protocols. NMR already occupies a central position in drug discovery for its use in...

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Detalles Bibliográficos
Publicado en:J Biomol NMR
Main Authors: Softley, Charlotte A., Bostock, Mark J., Popowicz, Grzegorz M., Sattler, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311382/
https://ncbi.nlm.nih.gov/pubmed/32524233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00322-0
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