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Paramagnetic NMR in drug discovery

The presence of an unpaired electron in paramagnetic molecules generates significant effects in NMR spectra, which can be exploited to provide restraints complementary to those used in standard structure-calculation protocols. NMR already occupies a central position in drug discovery for its use in...

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Dades bibliogràfiques
Publicat a:J Biomol NMR
Autors principals: Softley, Charlotte A., Bostock, Mark J., Popowicz, Grzegorz M., Sattler, Michael
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311382/
https://ncbi.nlm.nih.gov/pubmed/32524233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00322-0
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