Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations

PURPOSE: To investigate how induced tumor heterogeneity influences immune responses to radiotherapy (RT) with different proportions of mixed immune responsive and unresponsive tumor cells in a triple negative breast cancer model. It is hypothesized that studying the immune environment of mixed tumor...

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Publié dans:Clin Cancer Res
Auteurs principaux: Aguilera, Todd A., Elghonaimy, Eslam, Shehade, Hussein, Rafat, Marjan, Castellini, Laura, Jiang, Dadi, Kariolis, Mihalis, Koong, Albert C., Le, Quynh-Thu, Ellies, Lesley G., Rankin, Erinn B., Graves, Edward E., Giaccia, Amato J.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311370/
https://ncbi.nlm.nih.gov/pubmed/32098769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-4220
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