Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1

The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the histone methyltransferase Smyd1 regulates mitochondrial energetics. Here, we identified Perm1 (PPARGC-1 and ESRR-induced regulator, muscle sp...

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Pubblicato in:PLoS One
Autori principali: Oka, Shin-ichi, Sabry, Amira D., Horiuchi, Amanda K., Cawley, Keiko M., O’Very, Sean A., Zaitsev, Maria A., Shankar, Thirupura S., Byun, Jaemin, Mukai, Risa, Xu, Xiaoyong, Torres, Natalia S., Kumar, Anil, Yazawa, Masayuki, Ling, Jing, Taleb, Iosif, Saijoh, Yukio, Drakos, Stavros G., Sadoshima, Junichi, Warren, Junco S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310723/
https://ncbi.nlm.nih.gov/pubmed/32574189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234913
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