Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart

Smyd1, a muscle-specific histone methyltransferase, has established roles in skeletal and cardiac muscle development, but its role in the adult heart remains poorly understood. Our prior work demonstrated that cardiac-specific deletion of Smyd1 in adult mice (Smyd1-KO) leads to hypertrophy and heart...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Warren, Junco S., Tracy, Christopher M., Miller, Mickey R., Makaju, Aman, Szulik, Marta W., Oka, Shin-ichi, Yuzyuk, Tatiana N., Cox, James E., Kumar, Anil, Lozier, Bucky K., Wang, Li, Llana, June García, Sabry, Amira D., Cawley, Keiko M., Barton, Dane W., Han, Yong Hwan, Boudina, Sihem, Fiehn, Oliver, Tucker, Haley O., Zaitsev, Alexey V., Franklin, Sarah
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2018
विषय:
PNAS Plus
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099878/
https://ncbi.nlm.nih.gov/pubmed/30061404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800680115
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