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Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis

The “stress” kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin-dependent protein kinase II (CaMKII), phosphorylate the Na(+) channel Nav1.5 subunit to regulate its function. However, how the channel regulation translates to ventricular conduction is poorly understood. We hypothesize...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Zaitsev, Alexey V., Torres, Natalia S., Cawley, Keiko M., Sabry, Amira D., Warren, Junco S., Warren, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620685/
https://ncbi.nlm.nih.gov/pubmed/30875259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00660.2018
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