MicroRNA-181a as novel liquid biopsy marker of central nervous system involvement in pediatric acute lymphoblastic leukemia

BACKGROUND: Refractory central nervous system (CNS) involvement is among the major causes of therapy failure in childhood acute leukemia. Applying contemporary diagnostic methods, CNS disease is often underdiagnosed. To explore more sensitive and less invasive CNS status indicators, we examined micr...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Egyed, Bálint, Kutszegi, Nóra, Sági, Judit C., Gézsi, András, Rzepiel, Andrea, Visnovitz, Tamás, Lőrincz, Péter, Müller, Judit, Zombori, Marianna, Szalai, Csaba, Erdélyi, Dániel J., Kovács, Gábor T., Semsei, Ágnes F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310470/
https://ncbi.nlm.nih.gov/pubmed/32571344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02415-8
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