MicroRNA-181a as novel liquid biopsy marker of central nervous system involvement in pediatric acute lymphoblastic leukemia

BACKGROUND: Refractory central nervous system (CNS) involvement is among the major causes of therapy failure in childhood acute leukemia. Applying contemporary diagnostic methods, CNS disease is often underdiagnosed. To explore more sensitive and less invasive CNS status indicators, we examined micr...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Egyed, Bálint, Kutszegi, Nóra, Sági, Judit C., Gézsi, András, Rzepiel, Andrea, Visnovitz, Tamás, Lőrincz, Péter, Müller, Judit, Zombori, Marianna, Szalai, Csaba, Erdélyi, Dániel J., Kovács, Gábor T., Semsei, Ágnes F.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310470/
https://ncbi.nlm.nih.gov/pubmed/32571344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02415-8
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