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Chromatin run-on sequencing analysis finds that ECM remodeling plays an important role in canine hemangiosarcoma pathogenesis

BACKGROUND: Canine visceral hemangiosarcoma (HSA) is a highly aggressive cancer of endothelial origin that closely resembles visceral angiosarcoma in humans, both clinically and histopathologically. Currently there is an unmet need for new diagnostics and therapies for both forms of this disease. Th...

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Publicado en:BMC Vet Res
Autores principales: Mukai, Chinatsu, Choi, Eunju, Sams, Kelly L., Klampen, Elena Zu, Anguish, Lynne, Marks, Brooke A., Rice, Edward J., Wang, Zhong, Choate, Lauren A., Chou, Shao-Pei, Kato, Yukinari, Miller, Andrew D., Danko, Charles G., Coonrod, Scott A.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310061/
https://ncbi.nlm.nih.gov/pubmed/32571313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02395-3
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