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miR-122/SIRT1 axis regulates chondrocyte extracellular matrix degradation in osteoarthritis

Background/Aims: MicroRNAs (miRNAs) are involved in the pathogenesis of osteoarthritis (OA). The present study aimed to investigate the potential function of miR-122 in the development of OA and its potential molecular mechanisms. Methods: The expression of miR-122, silent information regulator 1 (S...

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Publicat a:Biosci Rep
Autors principals: Bai, Yinwei, Chen, Kun, Zhan, Jianfeng, Wu, Mingxin
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308613/
https://ncbi.nlm.nih.gov/pubmed/32395770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20191908
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