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Sirt1 regulates apoptosis and extracellular matrix degradation in resveratrol-treated osteoarthritis chondrocytes via the Wnt/β-catenin signaling pathways

Osteoarthritis (OA) has become a major public health problem with the increased aging population. Previous studies have demonstrated that resveratrol (RES) was able to increase the level of sirtuin 1 (Sirt1) in OA chondrocytes. However, further investigations are required to elucidate the precise mo...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Liu, Shuan, Yang, Hongping, Hu, Bing, Zhang, Mingyong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704318/
https://ncbi.nlm.nih.gov/pubmed/29201214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5165
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