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CircSERPINE2 weakens IL-1β-caused apoptosis and extracellular matrix degradation of chondrocytes by regulating miR-495/TGFBR2 axis

The dysregulated circular RNAs (circRNAs) are relevant to the development of osteoarthritis (OA). The circRNA serpin family E member 2 (circSERPINE2) is dysregulated in OA, while the role and mechanism of circSERPINE2 in OA are largely unknown. The aim of our research is to explore how and whether c...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Autores principales: Zhang, Qingpu, Qiao, Xiaomiao, Xia, Wenwei
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610148/
https://ncbi.nlm.nih.gov/pubmed/33094798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201601
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