Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia

Antipsychotic drugs target primarily dopaminergic system which makes catechol-O-methyltransferase (COMT) an interesting target in studies searching for treatment response predictors in schizophrenia. The study assessed the association of the COMT rs4680 and rs4818 polymorphisms with therapeutic resp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Nikolac Perkovic, Matea, Sagud, Marina, Zivkovic, Maja, Uzun, Suzana, Nedic Erjavec, Gordana, Kozumplik, Oliver, Svob Strac, Dubravka, Mimica, Ninoslav, Mihaljevic Peles, Alma, Pivac, Nela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308339/
https://ncbi.nlm.nih.gov/pubmed/32572118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67351-5
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