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Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity
Cats are a critical pre-clinical model for studying adeno-associated virus (AAV) vector-mediated gene therapies. A recent study has described the high prevalence of anti-AAV neutralizing antibodies among domestic cats in Switzerland. However, our knowledge of pre-existing humoral immunity against va...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308316/ https://ncbi.nlm.nih.gov/pubmed/32572045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66596-4 |
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