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Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing

Adeno-associated virus (AAV) capsid engineering is an emerging approach to advance gene therapy. However, a systematic analysis on how each capsid amino acid contributes to multiple functions remains challenging. Here we show proof-of-principle and successful application of a novel approach, termed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Adachi, Kei, Enoki, Tatsuji, Kawano, Yasuhiro, Veraz, Michael, Nakai, Hiroyuki
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Pub. Group 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941020/
https://ncbi.nlm.nih.gov/pubmed/24435020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4075
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