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High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and Massively Parallel Sequencing

We have developed a high-resolution genomic mapping technique that combines transposon-mediated insertional mutagenesis with either capillary electrophoresis or massively parallel sequencing to identify functionally important regions of the Venezuelan equine encephalitis virus (VEEV) genome. We init...

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Detalhes bibliográficos
Main Authors: Beitzel, Brett F., Bakken, Russell R., Smith, Jeffrey M., Schmaljohn, Connie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954836/
https://ncbi.nlm.nih.gov/pubmed/20976195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001146
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