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Stimulation strength controls the rate of initiation but not the molecular organisation of TCR-induced signalling
Millions of naïve T cells with different TCRs may interact with a peptide-MHC ligand, but very few will activate. Remarkably, this fine control is orchestrated using a limited set of intracellular machinery. It remains unclear whether changes in stimulation strength alter the programme of signalling...
Tallennettuna:
| Julkaisussa: | eLife |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
eLife Sciences Publications, Ltd
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7308083/ https://ncbi.nlm.nih.gov/pubmed/32412411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53948 |
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