Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks

[Image: see text] In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here cyclic oligochalcogenides (COCs), are covalently attached to lysines of wild-type streptavidin....

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: López-Andarias, Javier, Saarbach, Jacques, Moreau, Dimitri, Cheng, Yangyang, Derivery, Emmanuel, Laurent, Quentin, González-Gaitán, Marcos, Winssinger, Nicolas, Sakai, Naomi, Matile, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307903/
https://ncbi.nlm.nih.gov/pubmed/32109058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13621
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