Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks

[Image: see text] In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here cyclic oligochalcogenides (COCs), are covalently attached to lysines of wild-type streptavidin....

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: López-Andarias, Javier, Saarbach, Jacques, Moreau, Dimitri, Cheng, Yangyang, Derivery, Emmanuel, Laurent, Quentin, González-Gaitán, Marcos, Winssinger, Nicolas, Sakai, Naomi, Matile, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307903/
https://ncbi.nlm.nih.gov/pubmed/32109058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13621
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