Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks

[Image: see text] In this report, cell-penetrating streptavidin (CPS) is introduced to exploit the full power of streptavidin–biotin biotechnology in cellular uptake. For this purpose, transporters, here cyclic oligochalcogenides (COCs), are covalently attached to lysines of wild-type streptavidin....

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Vydáno v:J Am Chem Soc
Hlavní autoři: López-Andarias, Javier, Saarbach, Jacques, Moreau, Dimitri, Cheng, Yangyang, Derivery, Emmanuel, Laurent, Quentin, González-Gaitán, Marcos, Winssinger, Nicolas, Sakai, Naomi, Matile, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307903/
https://ncbi.nlm.nih.gov/pubmed/32109058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13621
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